AMIDE PROTON TRANSFER MRI SIGNAL AS A SURROGATE BIOMARKER OF ISCHEMIC STROKE RECOVERY IN PATIENTS WITH SUPPORTIVE TREATMENT

Amide Proton Transfer MRI Signal as a Surrogate Biomarker of Ischemic Stroke Recovery in Patients With Supportive Treatment

Background: Amide proton transfer (APT) MR imaging has shown great potential in the evaluation of stroke severity because of its sensitivity to acid environments.However, this promising MRI technique has not been used to assess treatment efficacy with regard to stroke recovery.Purpose: To assess the therapeutic effect of supportive treatment in isc

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Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1.

Heterozygous loss-of-function mutation of the calcium sensing-receptor (CaSR), causes familial click here hypocalciuric hypercalcemia type 1 (FHH1), a typically benign condition characterized by mild hypercalcemia.In contrast, homozygous mutation of this dimer-forming G-protein coupled receptor manifests as the lethal neonatal severe hyperparathyro

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The relationship of poetry and prose in old Serbian literature

This work is pointing out relations between poetry and prose in contemporary understanding of this problem, on one hand, and the comprehension of these relations in Serbian medieval literarary works, on the other hand.Literature, which was created in contemporary, modern period, is making clear difference in relations between poetry and prose, whil

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Comparative Chloroplast Genomics of Dipsacales Species: Insights Into Sequence Variation, Adaptive Evolution, and Phylogenetic Relationships

In general, the chloroplast genomes of angiosperms are considered to be highly conserved and affected little by adaptive evolution.In this study, we tested this hypothesis based on sequence differentiation and adaptive variation in the plastid genomes in the order Dipsacales.We sequenced the plastid genomes of one Adoxaceae species and six Caprifol

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